Medicinal Natural Products

Aim

The course aims to provide knowledge and understanding of organic chemistry, with emphasis on natural products and demonstrate the relationship between molecular structure and reactivity of the various transformations After completing this course the student

• have basic knowledge in natural product chemistry: structure, classification and biosynthesis of secondary metabolites
• can make connection between the reactions and mechanisms that apply to both synthetic chemistry biosynthesis • have knowledge of the medically important natural product origin, production, and identification, control and use
• have knowledge of medical uses and effects inc. toxicity of herbal remedies
• have knowledge of modern analytical methods for identification of natural products
• use laboratory organic analysis and synthesis techniques and be able to explain how chemicals are used in an environmentally way for sustainable development

Content

The course covers the basic theory of molecular structure, mechanisms and sterokemi with special emphasis on natural products. Biosynthesis of secondary metabolites from a chemical point of view and examples of their function in living material, organic reactions in terms of binding and reaction types and comparison with biosynthetic processes .. Furthermore, synthesis planning and strategy for the synthesis of natural products and pharmaceuticals, as well as methods for isolation and analysis of natural products . The laboratory sessions are designed to provide basic knowledge in organic chemical methodology and includes synthesis, and identification and analysis of organic compounds of biosynthetic origin.