Imaging and Ubiquitous Biosensing

Aim

The students will be trained to interpret the phenomena behind different detection approaches, to associate detected signals with multidimensional representation schemes and their related data structures and to handle this information to produce target evaluations. Guided by the examiner the students will plan, conduct and present a short (bio)sensing project based on one of the studied techniques. Upon this course the students should be able to:

• Understand different detection principles involved in imaging and ubiquitous (bio) sensing methods.
• Associate detected signals with multidimensional representation schemes and their data structures.
• Understand evaluation schemes and processing.
• Plan, conduct, report and present a imaging and/or ubiquitous (bio)sensing experiment.

Content

An introduction to imaging methods for bio and chemical sensing exploiting diverse optical and electrical phenomena and instrumentation strategies for ubiquitous sensing. Among these methods imaging systems for evaluation of colorimetric assays, reflective quick tests and arrays of fluorescent indicators are studied. Imaging versions of optical techniques for non-labelled assays such as ellipsometry and surface plasmon resonance, and field effect imaging detection in gas phase (SLPT) and solution (LAPS) are considered among others. Diverse approaches for distributed chemical analysis, home tests and point of care determinations are also considered with special attention to ubiquitous instrumentation such as lab-on-a-disk, odour identification with desktop scanners and computer screen photo-assisted techniques (CSPT). The focus of the course is on the measuring strategies and the information processing and includes the necessary instruction on Matlab programming.