Biomedical Optics

Aim

The course should provide a possibility for the student to acquire knowledge about the physical properties of light and its impact and interaction with biological tissue. After passing the course the student should be able to

• describe and choose suitable light sources, detectors and wavelengths applicable to specific medical applications and demands.
• derive and apply fundamental processes of light interaction with biological tissue.
• describe analytical and statistical light interaction models.
• describe, model, value and verify light-tissue interaction models.
• apply light-tissue interaction models for diagnostic and therapeutic use.
• describe, apply and value coherent and incoherent light source applications and dynamic light scattering applications.

Content

Optical properties of biological tissue. Measurement of tissue optical properties. Light transport in tissue. The therapuetic window. Light transport modelling and simulation. Applications with: diffuse reflectans spectroscopy, hyperspectral imaging, flourescense spectroscopy, molecular imaging, multiphoton excitation, optical coherence tomography, photoacoustic imaging, laser Doppler imaging, etc.